NEWS
Latest insights in pharmacology
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Severe drug interactions challenge COVID-19 Treatment – nirmatrelvir/ritonavir and tacrolimus require special attention
Up to 90% of patients treated with NMV/r face potential drug interactions.
- Science to Practice

NSAIDs to be avoided during the second half of pregnancy
NSAIDs should be avoided from mid-pregnancy onwards due to increased risks for the fetus.
- Science to Practice

Why do I need decision support in pharmacotherapy?
Safe pharmacotherapy starts with the right decision.
Medbase brings European experts together at EACPT 2025 to explore the future of clinical decision support
- Blog

False penicillin allergy labels are common – but solutions exist
Over 95% of penicillin allergy labels are incorrect – yet millions still avoid effective treatments.
- Science to Practice

Semaglutide (Ozempic) use during breastfeeding – concerns related to rapid weight loss, not the drug itself
Semaglutide is unlikely to enter breast milk and was not detected in a recent study.
- Science to Practice

Medbase strengthens its presence in the DACH region – welcome, Stefan Bodensteiner
We are pleased to welcome Stefan Bodensteiner to Medbase as our new Sales Manager for Germany, Austria and Switzerland.
- Our People

Is my patient cheating?
Even patients who follow their prescribed medication regimen may experience vastly different drug responses, from life-threatening adverse effects to complete lack of efficacy—highlighting the critical role of factors like drug-drug interactions, organ function, and genetic variability in treatment outcomes.
- Science to Practice

Increased risk of hospitalisation due to drug interactions in older adults
Drug interactions in older adults can lead to serious adverse events, longer hospital stays, and reduced quality of life.
- Science to Practice

Valproic acid and reproductive risks – the full story has not yet been told
Recent research indicates no evidence linking paternal valproic acid use before conception to increased risks of congenital malformations or neurodevelopmental disorders in offspring. Current data does not support major concerns.
- Science to Practice

All hope is not lost – tackling the global kidney disease burden with new therapeutics
New therapies, like SGLT2 inhibitors and GLP-1 receptor agonists, offer hope by slowing kidney disease progression and improving outcomes.
- Science to Practice

Tetracycline antibiotics may be used for up to three weeks also when breastfeeding
Tetracycline antibiotics can be used for up to three weeks during breast-feeding, as low milk excretion and minimal reported adverse effects have extended the recommended use.
- Science to Practice

Why should I bother with pharmacogenetics?
At least one actionable pharmacogenetic mutation is present in 97-99% of population (1,2) and more than half of them had three or more mutations (2).
- Science to Practice

Herbal products containing ashwagandha and turmeric/curcumin linked to liver injury
Ashwagandha may cause cholestatic hepatitis and elevated liver enzymes.
- Science to Practice

Genetic variability affects outcomes of drug therapy
Drug therapies don’t always work as expected. For some patients, the drugs have no effect, while others may experience severe adverse reactions.
- PROF. MIKKO NIEMI
- Interview

“Our product development is foresighted”
Markus Jansén, M.Sc. (Tech.), began his new role in April, motivated by the meaningful impact of his work.
- Our People
- CPO MARKUS JANSÉN

Vaaka Partners to invest in Medbase
Finland is exceptionally advanced in utilising user-friendly, high-quality drug information in everyday clinical work. This is largely due to…
- Interview